upsies

In real, traceable use. Part of the curated seed collection; community review is coming.

Meaning · English

Synonym of party pills.

Register: slang

Where it’s used: Used American English

Examples

The Rolling Stones cut a record called “Mother’s Little Helpers.’[’] An innocuous title? You bet it was, but the lyrics revealed that “Mother’s Little Helpers” are the “upsies and downsies” that mom takes to get her through the day. The “upsies” are the pep pills she takes when she wakes up and the

Usage example from English Wiktionary (CC BY-SA 4.0, retrieved 2026-07-30)

Sources & notes

Adapted from English Wiktionary (CC BY-SA 4.0, retrieved 2026-07-30 via kaikki.org).

Common questions

What does “upsies” mean?

Synonym of party pills.

Is “upsies” formal or informal?

upsies is generally slang.