mainline
In real, traceable use. Part of the curated seed collection; community review is coming.
Meaning · English
To inject (a drug) directly into a vein.
Register: slang
Where it’s used:
Used
American English
Examples
The patient skinpopped for 1½ years and then started to mainline heroin.
Usage example from English Wiktionary (CC BY-SA 4.0, retrieved 2026-07-30)
Sources & notes
Adapted from English Wiktionary (CC BY-SA 4.0, retrieved 2026-07-30 via kaikki.org).
Common questions
What does “mainline” mean?
To inject (a drug) directly into a vein.
Is “mainline” formal or informal?
mainline is generally slang.